DavMail
POP/IMAP/SMTP/Caldav/Carddav/LDAP exchange gateway allowing users to use any mail/calendar client with an Exchange server, even from the internet or behind a firewall through Outlook Web Access.
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Hyphanet
Anonymously share files, browse and publish _freesites_ (web sites accessible only through Hyphanet) and chat on forums.
Asterisk
Easy to use but advanced IP PBX system, VoIP gateway and conference server.
BigBlueButton
Supports real-time sharing of audio, video, slides (with whiteboard controls), chat, and the screen. Instructors can engage remote students with polling, emojis, and breakout rooms.
BuddyPress
Powerful plugin that takes your WordPress.org powered site beyond the blog with social-network features like user profiles, activity streams, user groups, and more.
Chitchatter
Peer-to-peer chat app that is serverless, decentralized, and ephemeral.
Discourse
Advanced forum / community solution based on Ruby and JS.